Try to make a habit of glancing at the bottles whenever you reset the ink counters.  You should get more than a dozen sets of ink jet cartridges worth of ink out of the 4 oz bottles so this isn't something you will have to do frequently.  When you refill the bottles, do not fill them all the way up to the brim.  Fill only to within 1 inch of the bottle cap.
If you do run the reservoir bottle and the cartridge dry, it is possible to re-prime the chamber by removing the cartridge from the printer, plugging the exit holes, and repeating the filling instructions.  However this will prove quite messy since you will be pumping some residue ink out of the cartridge in addition to the air.  It would be better to order a replacement modified virgin empty ink cartridge from us.